I think who we give the shards to matter in the next patch.
There's going to be a split off somewhere a for each of the remaining goddesses.
The mother will be a petulant brat as usual but you might be able to form a temporary alliance or truce. If you helped the potion hermit it might also affect things.
You may have the choice to reach out to various high priestesses Anna if you didn't alienate her too much might be an ally. There's also the Aramite high priestesses and what they will do.
The 'little girl' might appear once and help before running out of energy.
Lilith might inherit Mestan's RP points and help if they were high enough.